CBIO-4105 Bacteriophage Biology

The course explains the basic biology of bacteriophages and the relation with their hosts and other organisms. Developed through the combination of classes, article presentation and laboratory activities. During this course, lifecycles of the lytic cycle phages (T4), lysogenic (Lambda), ssDNA phages (M13 y phiX174) and RNA phages are studied, the distribution and importance of phages in ecosystems is also reviewed and discussed, as well as their utilization in phagotherapy, their impact in the bacterial pathogenicity (lysogenic conversion), bacteriophages genomic, among others. Lytic bacteriophages are isolated and purified in the lab practices, based on samples full of organic matter, and their genetic material is isolated and classified.